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00:00:06;11 , 00:00:09;07 , When tumors are first diagnosed,

00:00:09;07 , 00:00:12;16 , the first key question for the treating oncologist

00:00:12;16 , 00:00:15;22 , is whether this primary tumor

00:00:15;22 , 00:00:17;08 , has already shed its cells

00:00:17;08 , 00:00:19;21 , to distant locations within the body.

00:00:19;29 , 00:00:22;26 , The only criterion we've had for determining

00:00:22;26 , 00:00:25;01 , whether a lymph node is involved

00:00:25;01 , 00:00:27;09 , is by the size of the lymph node.

00:00:28;15 , 00:00:30;23 , In other words, if anything is small, 

00:00:30;24 , 00:00:32;02 , we tend to ignore it

00:00:32;02 , 00:00:34;12 , and call it something that is normal.

00:00:34;12 , 00:00:36;26 , Whereas, if something is bigger or enlarged,

00:00:36;26 , 00:00:38;20 , then we tend to call it a tumor.

00:00:38;20 , 00:00:40;27 , That doesn't sound very precise,

00:00:40;27 , 00:00:42;19 , and it's not very precise,

00:00:42;19 , 00:00:44;25 , but it's the best we've been able to do.