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00:00:05;25 , 00:00:07;21 , Okay, Dr. Kaufman, so this patient with

00:00:07;21 , 00:00:09;29 , prostate cancer that you referred to us

00:00:09;29 , 00:00:11;19 , for a nanoparticle exam...

00:00:11;19 , 00:00:14;08 , On the pre-contrast study, you can see that

00:00:14;08 , 00:00:16;09 , there is an enlarged node in the pelvis,

00:00:16;09 , 00:00:18;16 , and if you look at the size, it's about

00:00:18;16 , 00:00:21;11 , one centimeter by 2.3 centimeters.

00:00:21;11 , 00:00:23;24 , So by size, it is malignant 

00:00:23;24 , 00:00:28;03 , and it should be considered suspicious for tumor.

00:00:28;03 , 00:00:30;28 , But interestingly, after we gave the nanoparticles,

00:00:30;28 , 00:00:32;12 , you can see that the node has turned

00:00:32;12 , 00:00:34;19 , homogenously dark, which is a sign

00:00:34;19 , 00:00:37;06 , that the node is actually normal and benign,

00:00:37;06 , 00:00:38;22 , rather than it being malignant.

00:00:38;25 , 00:00:40;06 , We can now say

00:00:40;06 , 00:00:42;10 , that this is a normal lymph node,

00:00:42;10 , 00:00:44;17 , despite the fact that it's enlarged,

00:00:44;17 , 00:00:47;09 , and that changes the management completely,

00:00:47;09 , 00:00:50;11 , in a much more favorable way for the patient.